Popis knihy

This volume in the highly regarded Diagnostic Pathology series provides a clearer understanding of molecular pathology as it relates to the transformation and pathogenesis of cancer. Diagnostic Pathology: Molecular Oncology is the first reference to apply a practical and clinical approach to examining how molecular mutations affect common medical diseases. Additionally, it identifies the relevant and appropriate molecular tests to perform for a complete work-up in the era of molecular-targeted therapies. Easy to use and packed with outstanding illustrations, this is an essential resource for all pathologists or clinicians who need to keep up with the ever-evolving field of molecular medicine. Key FeaturesUp-to-date information on a variety of topicsNext-generation sequencing for determining gene mutationsDiagnostic use of soft tissue mutationsUse of solid tissue mutations such as EGFR, BRAF, and KRAS for diagnosis and treatment of different carcinomas and melanomaInterpreting newly found mutations in hematopathology such as MYD88 mutationsUnderstanding bioinformaticsGuidance on selecting the right test(s) at the right time for the right patientComparisons of molecular testing methods (i.e., FISH testing vs. cytogenetics)More than 2,000 images including H&E stains, immunostains, and FISH images